Nonlinear Pharmacokinetics of Topical Flurbiprofen Gel in a Phase I Study Among Chinese Healthy Adults.

Wending XiaoZhihong ZhuFeifan XieFeiyan LiuZeneng Cheng

Published in: Pharmaceutical research (2024)

The topical PDX-02 gel showed favorable safety and tolerability in both single and multiple dosing studies, with a less-than-dose-proportional nonlinear pharmacokinetics observed.

Keyphrases

wound healing
open label
hyaluronic acid
randomized controlled trial
case control
study protocol