Inpatient COVID-19 mortality has reduced over time: Results from an observational cohort.
Katie BechmanMark YatesKirsty MannDeepak NagraLaura-Jane SmithAndy I RutherfordAmit PatelJimstan PeriselnerisDavid WalderRichard J B DobsonZeljko KraljevicJames H T TeoWilliam BernalRichard BarkerJames B GallowaySam NortonPublished in: PloS one (2022)
There has been substantial improvements in COVID-19 mortality in the second wave, even accounting for demographics, comorbidity, and disease severity. Neither dexamethasone nor remdesivir appeared to be key explanatory factors, although there may be unmeasured confounding present.