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Atrophy, ultra-structural disorders, severe atrophy and degeneration of denervated human muscle in SCI and Aging. Implications for their recovery by Functional Electrical Stimulation, updated 2017.

Helmut KernCristian HoferStefan LöflerSandra ZampieriPaolo GargiuloAlfonc BabaAndrea MarcanteFrancesco PiccioneAmber PondUgo Carraro
Published in: Neurological research (2017)
Human myofibers survive permanent denervation longer than generally accepted and they respond to h-bFES beyond the stage of simple atrophy. Furthermore, long-term denervation/reinnervation events occur in elderly people and are part of the mechanisms responsible for muscle aging and again h-bFES was beneficial in delaying aging decay.
Keyphrases
  • endothelial cells
  • spinal cord injury
  • skeletal muscle
  • induced pluripotent stem cells
  • pluripotent stem cells
  • early onset
  • high resolution