Patent foramen ovale closure in stroke patients with migraine in the CLOSE trial. The CLOSE-MIG study.
Jean-Louis MasBenoît GuillonAnaïs Charles-NelsonValérie DomigoLaurent DerexEvelyne MassardierCaroline ArquizanFabrice VuillierSerge TimsitYannick BéjotOlivier DetanteDenis SablotCéline GuidouxIgor Paul SibonNelly Dequatre-PonchelleEmmanuel TouzéSandrine CanapleSonia AlamowitchPierre AubryEmmanuel TeigerGeneviève DerumeauxGilles Chatelliernull nullPublished in: European journal of neurology (2021)
In young and middle-aged adults with PFO-associated cryptogenic stroke and migraine, PFO closure plus antiplatelet therapy did not reduce the mean annual number of migraine attacks compared to antiplatelet therapy alone, in migraine patients both with and without aura.
Keyphrases
- antiplatelet therapy
- acute coronary syndrome
- percutaneous coronary intervention
- middle aged
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- coronary artery disease
- atrial fibrillation
- peritoneal dialysis
- study protocol
- prognostic factors
- randomized controlled trial
- phase iii
- patient reported outcomes
- blood brain barrier