Pharmacokinetics of oral versus intravenous ibuprofen for closure of patent ductus arteriosus: A pilot randomised controlled study.
Priyantha Ebenezer EdisonSylvia ChenCheo Lian YeoJohn C AllenWoei Bing PoonVijayendra R BaralBalram ChowbayPublished in: Journal of paediatrics and child health (2021)
This exploratory study demonstrates comparable pharmacokinetics of PO and IV formulations of ibuprofen in preterm neonates. Larger prospective studies are required to validate these findings.