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Disrupted Binding of Cystathionine γ-Lyase to p53 Promotes Endothelial Senescence.

Jiong HuMatthias S LeisegangMario LoosoMaria-Kyriaki DrekoliaJanina WittigJanina MettnerChristina KarantanouAnastasia KyselovaGabrijela DumbovićXiaoming LiYuanyuan LiStefan GüntherDavid JohnMauro SiragusaSven ZukunftJames OoIlka WittigSusanne S HilleAndreas WeigertStefan KnappRalf P BrandesOliver J MüllerAndreas PapapetropoulosFragiska SigalaGergana DobrevaBaktybek KojonazarovIngrid FlemingSofia-Iris Bibli
Published in: Circulation research (2023)
Aging-associated impairment of vascular repair is partly determined by the vasoprotective enzyme CSE.
Keyphrases
  • endothelial cells
  • dna damage
  • stress induced
  • dna binding
  • binding protein
  • oxidative stress
  • transcription factor