Increased blood CD226 - inflammatory monocytes with low antigen presenting potential correlate positively with severity of hemorrhagic fever with renal syndrome.
Kang TangYongli HouLinfeng ChengYu-Si ZhangJuan LiQi QinXuyang ZhengXiaozhou JiaChunmei ZhangRan ZhuangYun ZhangBoquan JinLihua ChenYing MaPublished in: Annals of medicine (2023)
iMOs increased during HTNV infection and the decrease in CD226 hampered the expression of HLA-DR/DP/DQ and CD80, which may promote the immune escape of HTNV and exacerbate clinical symptoms.