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[Predictive markers of immunotherapy in cervical cancer].

E M OlyushinaL E ZavalishinaYulia Yu AndreevaO A KuznetsovaL V MoskvinaG A Frank
Published in: Arkhiv patologii (2023)
A positive PD-L1 status is determined in a significant number of cases of CC, regardless of most of the studied clinical and morphological characteristics; there is a statistically significant relationship between PD-L1 expression and the degree of tumor differentiation and TILs. It has been shown that CC with the MSI/dMMR phenomenon is characterized by a positive PD-L1 status. The authors consider it necessary to study the expression of PD-L1 in patients with cervical carcinomas in order to determine the possibility of prescribing personalized therapy with immune checkpoint inhibitors.
Keyphrases
  • primary care
  • poor prognosis
  • high grade
  • emergency department
  • stem cells
  • binding protein
  • adverse drug
  • drug induced