Role of endogenous glucagon-like peptide-1 enhanced by vildagliptin in the glycaemic and energy expenditure responses to intraduodenal fat infusion in type 2 diabetes.
Cong XieXuyi WangKaren Louise JonesMichael HorowitzZilin SunTanya J LittleChristopher K RaynerChinmay S MarathePublished in: Diabetes, obesity & metabolism (2019)
In well-controlled T2DM during intraduodenal fat infusion, vildagliptin lowered plasma glucose and glucagon, and tended to decrease energy expenditure, effects that were mediated by endogenous GLP-1.