Association of Plasma Methylglyoxal Increase after Myocardial Infarction and the Left Ventricular Ejection Fraction.
Stefan HeberPaul M HallerAttila KissBernhard JägerKurt HuberMichael J M FischerPublished in: Biomedicines (2022)
Considering these observational data, it is plausible that the preclinical finding of MG generation after AMI negatively affecting the LVEF also applies to humans. Inhibition of MG generation or MG scavenging might provide a novel therapeutic strategy to target post-AMI myocardial remodeling and dysfunction.
Keyphrases
- ejection fraction
- left ventricular
- aortic stenosis
- acute myocardial infarction
- heart failure
- hypertrophic cardiomyopathy
- electronic health record
- oxidative stress
- cardiac resynchronization therapy
- transcatheter aortic valve replacement
- left atrial
- big data
- aortic valve
- cross sectional
- machine learning
- stem cells
- acute coronary syndrome
- bone marrow