Clinical prediction models for mortality in patients with covid-19: external validation and individual participant data meta-analysis.
Valentijn M T de JongRebecca Z RoussetNeftalí Eduardo Antonio-VillaArnoldus G BuenenBen Van CalsterOmar Yaxmehen Bello-ChavollaNigel J BrunskillVasa CurcinJohanna A A G DamenCarlos A Fermín-MartínezLuisa Fernandez-ChirinoDavide FerrariRobert C FreeRishi K GuptaPranabashis HaldarPontus HedbergSteven Kwasi KorangSteef KurstjensRon KustersRupert W MajorLauren MaxwellRajeshwari NairPontus NauclerTri-Long NguyenMahdad NoursadeghiRossana M RosaFelipe SoaresToshihiko TakadaFlorien Sophie-Anne van RoyenMaarten van SmedenLaure WynantsMartin Modráknull nullFolkert W. AsselbergsMarijke Linschotennull nullKarel G M MoonsThomas P A DebrayPublished in: BMJ (Clinical research ed.) (2022)
The prognostic value of the included models varied greatly between the data sources. Although the Knight 4C Mortality Score and Wang clinical model appeared most promising, recalibration (intercept and slope updates) is needed before implementation in routine care.