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Quantifying the advantages of conducting a prospective meta-analysis (PMA): a case study of early childhood obesity prevention.

Anna Lene SeidlerK E HunterD EspinozaS MihrshahiL M Askienull null
Published in: Trials (2021)
Prospective planning led to greater outcome harmonisation and greater power to detect intervention effects, while maintaining acceptable variation in trial designs and populations, which improved external validity. Recommendations for future PMA include more detailed harmonisation of outcome measures and careful pre-specification of analyses to avoid research waste by unnecessary over-collection of data.
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