m6A Modification Promotes EMT and Metastasis of Castration-Resistant Prostate Cancer by Upregulating NFIB.

Feng Shu Hao Liu Xiaohui Chen Ye Liu Jiangli Zhou Lei Tang Wanwei Cao Shanshan Yang Yili Long Rongna Li Hao Wang Hong-Sheng Wang Guanmin Jiang

Published in: Cancer research (2024)

NFIB upregulation mediated by increased m6A levels in AR-negative castration-resistant prostate cancer regulates transcription of EMT-related factors to promote metastasis, providing a potential therapeutic target to improve prostate cancer treatment.

Keyphrases

epithelial mesenchymal transition
prostate cancer
poor prognosis
signaling pathway
cell proliferation
transcription factor
climate change
long non coding rna