Noninvasive, longitudinal imaging-based analysis of body adipose tissue and water composition in a melanoma mouse model and in immune checkpoint inhibitor-treated metastatic melanoma patients.
Wolfgang M ThaissSergios GatidisTina SartoriusJürgen MachannAndreas PeterThomas K EigentlerKonstantin NikolaouBernd J PichlerManfred KneillingPublished in: Cancer immunology, immunotherapy : CII (2020)
MRI-based segmentation of fat and water contents adds essential additional information for monitoring the development of CC in mice and metastatic melanoma patients during CIT or other treatment approaches.
Keyphrases
- adipose tissue
- end stage renal disease
- newly diagnosed
- chronic kidney disease
- mouse model
- ejection fraction
- magnetic resonance imaging
- peritoneal dialysis
- type diabetes
- healthcare
- computed tomography
- mass spectrometry
- patient reported outcomes
- metabolic syndrome
- contrast enhanced
- fatty acid
- convolutional neural network
- combination therapy
- patient reported
- high fat diet induced
- fluorescence imaging