Characterization of the role of HCN channels in β3-adrenoceptor mediated rat bladder relaxation.

Mahendra KashyapNaoki YoshimuraPhillip P SmithMichael ChancellorPradeep Tyagi

Published in: Bladder (San Francisco, Calif.) (2015)

Species-specific differences were noted in expression of HCN channels in bladder. Opposing effects ZD7288 and Lamotrigine in the action of β3-AR agonist demonstrate possible functional interaction of HCN channels and β3-AR in detrusor contractility.

Keyphrases

spinal cord injury
poor prognosis
oxidative stress
urinary tract
smooth muscle
binding protein
long non coding rna