High intimal flap mobility assessed by intravascular ultrasound is associated with better short-term results after TEVAR in chronic aortic dissection.
Julia LortzMaria PapathanasiouChristos RammosMartin SteinmetzAlexander LindKonstantinos TsagakisThomas SchlosserHeinz JakobTienush RassafRolf Alexander JánosiPublished in: Scientific reports (2019)
Thoracic endovascular aortic repair (TEVAR) in chronic aortic dissection remains controversial. We analysed whether a high intimal flap mobility (IFM) of the dissection membrane has an impact on aortic remodelling after TEVAR in chronic Type B aortic dissection. Patients undergoing TEVAR with intravascular ultrasound (IVUS) were analysed and IFM was calculated. High IFM was defined as maximum flap amplitude >3 mm. For determining aortic remodelling, the degree of true lumen (TL) expansion was analysed in the last available follow-up CT. Fifty-two patients (63.6 ± 15.4 years) with a mean follow-up of 26.6 ± 20.7 months were analysed. The mobile flap group (n = 29) showed higher absolute TL expansion at the distal stent-graft (5.9 ± 3.1 vs. 3.3 ± 5.4 mm; p = 0.036) and a higher increase in TL diameter (18 ± 10 vs. 9 ± 15%; p = 0.017) compared to the non-mobile group (n = 23). Basic TEVAR-related outcome characteristics were comparable, but the mobile intimal flap group showed a lower re-intervention rate (3 vs. 8pts.; p = 0.032) in chronic dissections. High IFM in chronic Type B aortic dissection is linked to improved aortic remodelling and is associated with a lower re-intervention rate over time. IVUS assessment of IFM in chronic Type B aortic dissection might be helpful in identifying patients with better remodelling after TEVAR.
Keyphrases
- aortic dissection
- randomized controlled trial
- magnetic resonance imaging
- patients undergoing
- end stage renal disease
- breast reconstruction
- soft tissue
- heart failure
- computed tomography
- chronic kidney disease
- ejection fraction
- spinal cord
- spinal cord injury
- drug induced
- pulmonary hypertension
- newly diagnosed
- ultrasound guided
- left ventricular
- optical coherence tomography
- atrial fibrillation
- pulmonary arterial hypertension
- image quality