Prediction of H3 K27M-mutant in midline gliomas by magnetic resonance imaging: a systematic review and meta-analysis.

Tiantian HuaZhizheng ZhuoYunyun DuanXindi LiHongqiu GuSven HallerPeng ZhangXing LiuLiwei ZhangYaou Liu

Published in: Neuroradiology (2022)

This meta-analysis demonstrated a clinical value of MRI to predict H3 K27M-mutant in midline gliomas with a pooled sensitivity of 0.78 and specificity of 0.85.

Keyphrases

magnetic resonance imaging
high grade
systematic review
contrast enhanced
wild type
meta analyses
diffusion weighted imaging
computed tomography
clinical trial
magnetic resonance
randomized controlled trial
case control
structural basis
study protocol
double blind