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Mental illness and cardiovascular health: observational and polygenic score analyses in a population-based cohort study.

R R VeenemanJentien M VermeulenM BialasA K BhamidipatiAbdel AbdellaouiMarcus R MunafoDamiaan A J P DenysConnie R BezzinaKarin J H VerweijRafik TadrosJorien L Treur
Published in: Psychological medicine (2023)
Our study shows widespread associations of (genetic liability to) mental illness (primarily depressive disorder) with CVD, even after confounder adjustment. Future research should focus on clarifying potential causal pathways between mental illness and CVD.
Keyphrases
  • mental illness
  • mental health
  • bipolar disorder
  • genome wide
  • current status
  • cross sectional
  • gene expression
  • risk assessment