Increased Expression of Oct4, Nanog and CD24 Predicts Poor Response to Chemo-Radiotherapy and Unfavourable Prognosis in Locally Advanced Oral Squamous Cell Carcinoma.
Sridhar MishraVandna TiwariAditi AroraSeema GuptaNidhi AnandNuzhat HussainPublished in: Asian Pacific journal of cancer prevention : APJCP (2020)
Expressions of Oct4, Nanog and CD24 have significant association with treatment response and survival in patients with locally advanced OSCC treated with neoadjuvant chemo-radiation. Survival of these patients is significantly affected by ypN stage, ypTNM stage, expression of all three biomarkers, clinical and pathological response to neoadjuvant therapy.<br />.
Keyphrases
- locally advanced
- rectal cancer
- neoadjuvant chemotherapy
- squamous cell carcinoma
- radiation therapy
- phase ii study
- poor prognosis
- newly diagnosed
- end stage renal disease
- optical coherence tomography
- ejection fraction
- prognostic factors
- diabetic retinopathy
- peritoneal dialysis
- binding protein
- clinical trial
- stem cells
- free survival
- drug delivery
- mesenchymal stem cells
- patient reported outcomes
- nk cells
- embryonic stem cells
- optic nerve
- patient reported