Prostate Specific Membrane Antigen Expression in a Syngeneic Breast Cancer Mouse Model.
Aditi A ShirkeJing WangGopolakrishnan RamamurthyArpan MahantyEthan WalkerLifang ZhangAbhiram PanigrahiXinning WangJames P BasilionPublished in: Molecular imaging and biology (2024)
The selective uptake of PSMA-1-Pc413 in these cancer tissues as well as the characterization and validation of PSMA expression on neovasculature in this syngeneic 4T1 model emphasizes their potential for advancements in targeted therapies and imaging techniques for BCa. PSMA holds great promise as an oncogenic target for BCa and its associated metastases.
Keyphrases
- pet ct
- pet imaging
- poor prognosis
- mouse model
- prostate cancer
- high resolution
- papillary thyroid
- binding protein
- gene expression
- long non coding rna
- transcription factor
- positron emission tomography
- big data
- risk assessment
- squamous cell
- machine learning
- childhood cancer
- mass spectrometry
- human health
- artificial intelligence
- breast cancer risk