The Emergence and Progression of Motor Dysfunction in Individuals at Risk of Parkinson's Disease.

Cristina Simonet Philipp MahlknechtKathrin MariniKlaus SeppiAneet GillJonathan P BestwickAndrew J LeesGavin GiovannoniAnette-Eleonore Schrag Alastair J Noyce

Published in: Movement disorders : official journal of the Movement Disorder Society (2023)

Risk estimates using the PREDICT-PD algorithm were associated with the occurrence of sub-threshold parkinsonism, including bradykinesia and action tremor. The algorithm could also identify individuals whose motor examination experience a decline over time. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

Keyphrases

machine learning
parkinson disease
deep learning
risk assessment
deep brain stimulation
oxidative stress
neural network
randomized controlled trial