No difference in human mast cells derived from peanut allergic versus non-allergic subjects.

Lau F LarsenNanna Juel-BergAnker HansenKirsten S HansenE N Clare MillsRonald van ReeMadeleine RådingerLars K PoulsenBettina M Jensen

Published in: Immunity, inflammation and disease (2018)

The molecular and stimulus-response profile revealed that PBdMC from peanut allergic subjects differently express IL-31 compared to non-allergic subjects. However, since only one altered parameter was found among 893 investigated, it is still questionable if the pathophysiological mechanisms of peanut allergy are revealed in PBdMC.

Keyphrases

allergic rhinitis
atopic dermatitis
endothelial cells
single cell
induced pluripotent stem cells
high resolution
pluripotent stem cells