Comprehensive expressional analysis of chemosensitivity-related markers in large cell neuroendocrine carcinoma of the lung.

Yoichi Ohtaki Kyoichi Kaira Toshiki YajimaBilguun Erkhem-OchirOsamu KawashimaMitsuhiro Kamiyoshihara Hitoshi Igai Ryoichi OnozatoTakashi IbeTakayuki KosakaSeshiru NakazawaToshiteru NagashimaTetsunari OyamaKen Shirabe

Published in: Thoracic cancer (2021)

These findings suggest that elevated Topo-II and TS expression may contribute to poor outcomes through protumoral biology in patients with LCNEC, and elevated VEGFR2 expression might negatively impact tumor immune reactions in LCNEC.

Keyphrases

poor prognosis
binding protein
cell therapy
long non coding rna
type diabetes
endothelial cells
weight loss