The diagnostic performance of CT and MRI for detecting extranodal extension in patients with head and neck squamous cell carcinoma: a systematic review and diagnostic meta-analysis.
Sang Ik ParkJeffrey P GuenetteChong Hyun SuhGlenn J HannaSae Rom ChungJung Hwan BaekJeong Hyun LeeYoung Jun ChoiPublished in: European radiology (2020)
• Pooled sensitivity and specificity were 73% and 83% for CT and 60% and 96% for MRI without significant difference. • Pooled specificity was lower for HPV+ OPSCC than for HPV‑ oral cavity cancer or all HNSCC (74% vs. 87%, p = 0.01), likely due to central node necrosis. • Central node necrosis showed higher sensitivity (81% vs. 51%; p = 0.02), while infiltration of adjacent planes showed higher specificity (94% vs. 65%; p = 0.03).
Keyphrases
- contrast enhanced
- magnetic resonance imaging
- systematic review
- computed tomography
- magnetic resonance
- lymph node
- high grade
- dual energy
- diffusion weighted imaging
- image quality
- structural basis
- papillary thyroid
- meta analyses
- positron emission tomography
- cervical cancer screening
- randomized controlled trial
- case control
- squamous cell carcinoma