Genetic Markers of Brown Adipose Tissue Identity and In Vitro Brown Adipose Tissue Activity in Humans.

Emmani B M NascimentoLauren M SparksAdeline DivouxMarike W van GisbergenEvie P M BroedersJohanna A JörgensenGert SchaartNicole D BouvyWouter D van Marken LichtenbeltPatrick Schrauwen

Published in: Obesity (Silver Spring, Md.) (2017)

Differentiated adipocytes derived from human BAT maintain intrinsic characteristics of the donor. High ZIC1 mRNA does not necessarily reflect high BAT activity.

Keyphrases

adipose tissue
insulin resistance
high fat diet
endothelial cells
genome wide
gene expression
induced pluripotent stem cells
dna methylation
pluripotent stem cells
copy number