Assessing evolutionary and developmental transcriptome dynamics in homologous cell types.

Published in: Developmental dynamics : an official publication of the American Association of Anatomists (2021)

We present an approach to identify evolutionary and developmental dynamics in gene co-expression modules during patterning-relevant stages of homologous cell type specification using single-cell RNA-sequencing data.

Keyphrases

single cell
rna seq
genome wide
dna repair
dna damage
high throughput
poor prognosis
cell fate
dna methylation
copy number
electronic health record
big data
stem cells
binding protein
oxidative stress
data analysis
genome wide identification
cell therapy