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Robust generation of human-chambered cardiac organoids from pluripotent stem cells for improved modelling of cardiovascular diseases.

Beatrice Xuan HoJeremy Kah Sheng PangYing ChenYuin-Han LohOmer AnHenry He YangVeerabrahma Pratap SeshachalamJudice L Y KohWoon-Khiong ChanShi Yan NgBoon-Seng Soh
Published in: Stem cell research & therapy (2022)
Our findings shed novel insights into the role of progenitors in CCO formation and pave the way for the robust generation of cardiac organoids, as a platform for future applications in disease modelling and drug screening in vitro.
Keyphrases
  • pluripotent stem cells
  • induced pluripotent stem cells
  • cardiovascular disease
  • left ventricular
  • endothelial cells
  • high throughput
  • current status
  • emergency department
  • coronary artery disease