Safety and efficacy of mesenchymal stem cells therapy in the treatment of rheumatoid arthritis disease: A systematic review and meta-analysis of clinical trials.

Luz Estella MesaJosue Guillermo LópezLucas López QuicenoFreddy Andrés Barrios-Arroyave Karolynn HalpertJhyld C Camacho

Published in: PloS one (2023)

This Systematic review and meta-analysis showed a favorable safety profile, without life-threatening events in subjects with RA, and a trend toward clinical efficacy that must be confirmed through high-quality RCTs, considerable sample size, and extended follow-up in subjects with RA.

Keyphrases

rheumatoid arthritis
disease activity
mesenchymal stem cells
clinical trial
ankylosing spondylitis
interstitial lung disease
systemic lupus erythematosus
umbilical cord
stem cells
randomized controlled trial
systemic sclerosis
phase ii
open label
study protocol