Prognostic Impact of PD-1 and Tim-3 Expression in Tumor Tissue in Stage I-III Colorectal Cancer.
Wentao KuaiXinjian XuJing YanWujie ZhaoYaxing LiBin WangNa YuanZhongxin LiYitao JiaPublished in: BioMed research international (2020)
In summary, upregulation of PD-1 and Tim-3 in stage I-III CRC tumor tissue could be associated with the poor prognosis of patients. Those patients with coexpression of PD-1 and Tim-3 may have a significantly worse prognosis.