Marked variability in bioactivity between commercially available bovine colostrum for human use; implications for clinical trials.
Raymond John PlayfordMeg CattellTania MarchbankPublished in: PloS one (2020)
Commercial colostrum products possess widely different bioactivity. Variation in heat exposure and/or proportion of day 0 colostrum content may contribute to this. Assessment of colostrum bioactivity has advantages to growth factor quantitation for quality control.
Keyphrases
- growth factor
- human milk
- quality control
- clinical trial
- endothelial cells
- low birth weight
- ms ms
- mass spectrometry
- liquid chromatography tandem mass spectrometry
- heat stress
- high performance liquid chromatography
- induced pluripotent stem cells
- pluripotent stem cells
- phase ii
- solid phase extraction
- preterm birth
- double blind