Ketamine mouthwash versus placebo in the treatment of severe oral mucositis pain in children with cancer: A randomized double-blind placebo-controlled trial.
Satya PrakashJagdish Prasad MeenaAditya Kumar GuptaSameer BakhshiThirumurthy VelpandianR M PandeyRachna SethPublished in: Pediatric blood & cancer (2020)
Among children on cancer chemotherapy with severe OM, ketamine mouthwash at a dose of 1 mg/kg did not significantly reduce OM pain. It did not decrease the need for rescue pain medications. Further research is warranted to test higher doses of ketamine for a clinically significant effect.
Keyphrases
- pain management
- chronic pain
- double blind
- papillary thyroid
- neuropathic pain
- young adults
- squamous cell
- clinical trial
- placebo controlled
- early onset
- squamous cell carcinoma
- randomized controlled trial
- lymph node metastasis
- childhood cancer
- spinal cord
- phase iii
- spinal cord injury
- locally advanced
- combination therapy
- phase ii