A randomized, open-label pharmacokinetic trial of tacrolimus extended-release dosing in obese de novo kidney transplant recipients.
Natalia M Jasiak-PanekEric WenzlerShree PatelJames J ThielkeKristin ProgarShitalben PatelShane BrandtYi-Jen HuangEnrico BenedettiPatricia M West-ThielkePublished in: Clinical transplantation (2019)
In a population of obese renal transplant recipients, comparable trough concentrations and overall exposure in both groups indicate that IBW may be preferred, as less initial drug was needed to attain adequate exposure.