Cytokine and hormonal regulation of bone marrow immune cell Wnt10b expression.

Fraser L CollinsNaiomy Deliz Rios-ArceLaura R McCabeNarayanan Parameswaran

Published in: PloS one (2017)

Our results demonstrate unique cell type- and sex-dependent effects on BMIC Wnt10b expression. Together, our results reveal myeloid cells in the bone marrow as an important source of Wnt10b under complex hormonal and cytokine regulation.

Keyphrases

bone marrow
poor prognosis
cell proliferation
stem cells
mesenchymal stem cells
induced apoptosis
cell cycle arrest
binding protein
acute myeloid leukemia
dendritic cells
single cell
endoplasmic reticulum stress
cell death