Effects of Akkermansia muciniphila and Faecalibacterium prausnitzii on serotonin transporter expression in intestinal epithelial cells.

Rezvan YaghoubfarAva BehrouziAbolfazl FatehSeyed Ali NojoumiFarzam VaziriShohreh KhatamiSeyed Davar Siadat

Published in: Journal of diabetes and metabolic disorders (2021)

The present results showed that A. muciniphila and F. prausnitzii, as well as their supernatants, increased the expression of SERT gene in Caco-2 cells. Therefore, they might be helpful in the microbiota-modulating treatment of inflammatory bowel diseases.

Keyphrases

poor prognosis
induced apoptosis
cell cycle arrest
long non coding rna
copy number
oxidative stress
combination therapy
cell death
endoplasmic reticulum stress