HMGA2 is a specific immunohistochemical marker for pleomorphic adenoma and carcinoma ex-pleomorphic adenoma.

Jeffrey K MitoVickie Y JoSimion I ChioseaPaola Dal CinJeffrey F Krane

Published in: Histopathology (2017)

HMGA2 expression is a highly specific (96.2%), but low-sensitivity (29.8%), marker for PA and CA ex-PA when compared with histological mimics, and is frequently associated with rearrangement of the HMGA2 locus.

Keyphrases

poor prognosis
binding protein
protein kinase