Identification of significant protein markers by mass spectrometry after co-treatment of cells with different drugs: An in vitro survey platform.
Ying-Jung WuChing-Hui HuangTusty-Jiuan HsiehWei-Lung TsengChi-Yu LuPublished in: Rapid communications in mass spectrometry : RCM (2020)
Using the proposed in vitro platform, significant protein markers of drug-drug interactions could be identified by mass spectrometry. This workflow can then help predict indicators of drug-drug interactions and associated adverse effects for increased safety in clinical prescriptions.
Keyphrases
- mass spectrometry
- liquid chromatography
- induced apoptosis
- high throughput
- gas chromatography
- protein protein
- capillary electrophoresis
- high resolution
- high performance liquid chromatography
- cell cycle arrest
- binding protein
- drug induced
- cross sectional
- adverse drug
- emergency department
- electronic health record
- cell death
- ms ms
- bioinformatics analysis