The CRYOSTAT2 trial: The rationale and study protocol for a multi-Centre, randomised, controlled trial evaluating the effects of early high-dose cryoprecipitate in adult patients with major trauma haemorrhage requiring major haemorrhage protocol activation.
Nicola S CurryRoss A DavenportJoanne LucasAlison DearyJonathan R BengerAntoinette EdwardsAmy EvansClaire FoleyLaura GreenStephen MorrisHelen L ThomasKarim BrohiSimon J StanworthPublished in: Transfusion medicine (Oxford, England) (2022)
This trial will provide firmer evidence to evaluate the effectiveness and cost-effectiveness of early high-dose cryoprecipitate alongside the standard MHP in major traumatic haemorrhage.