Mitral annulus disjunction is associated with adverse outcome in Marfan and Loeys-Dietz syndromes.
Monica ChivulescuKirsten Krohg-SørensenEsther ScheirlynckBeate R LindbergLars A DejgaardØyvind H LieThomas Helle-ValleEystein T SkjølsvikMette E EstensenThor EdvardsenPer S LingaasKristina Hermann HaugaaPublished in: European heart journal. Cardiovascular Imaging (2021)
MAD was highly prevalent in patients with MFS and LDS. MAD was a marker of severe disease including aortic events at younger age and need of mitral valve surgery. Screening patients with MFS an LDS for MAD may provide prognostic information and may be relevant in planning surgical intervention. Detection of MAD in patients with MFS and LDS may infer closer clinical follow-up from younger age.
Keyphrases
- mitral valve
- left ventricular
- aortic valve
- left atrial
- minimally invasive
- randomized controlled trial
- coronary artery bypass
- aortic dissection
- pulmonary artery
- healthcare
- loop mediated isothermal amplification
- aortic stenosis
- emergency department
- health information
- acute coronary syndrome
- coronary artery
- transcatheter aortic valve replacement
- ejection fraction
- quantum dots
- adverse drug
- pulmonary arterial hypertension