An in vitro anti-inflammatory effect of Thai propolis in human dental pulp cells.

Nutthapong Kantrong Jittranut Kumtawee Teerasak Damrongrungruang Subin Puasiri Anupong Makeudom Suttichai Krisanaprakornkit Pattama Chailertvanitkul

Published in: Journal of applied oral science : revista FOB (2023)

Upregulated COX-2 expression and enhanced PGE2 synthesis upon treatment with IL-1β in human dental pulp cells were suppressed by incubation with non-toxic doses of Thai propolis extract via involvement of the NF-kB activation. This extract could be therapeutically used as a pulp capping material due to its anti-inflammatory properties.

Keyphrases

anti inflammatory
induced apoptosis
endothelial cells
oxidative stress
cell cycle arrest
signaling pathway
poor prognosis
pi k akt
induced pluripotent stem cells
endoplasmic reticulum stress
cell death
inflammatory response
long non coding rna
nuclear factor
replacement therapy