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Predischarge Injectable Versus Oral Naltrexone to Improve Postdischarge Treatment Engagement Among Hospitalized Veterans with Alcohol Use Disorder: A Randomized Pilot Proof-of-Concept Study.

Angela Christina BuschMeenakshi DenduluriJoseph GlassScott HetzelShalu P GugnaniMichele GassmanDean KrahnBrienna DeyoRandall T Brown
Published in: Alcoholism, clinical and experimental research (2017)
Results indicate feasibility for larger, more definitive study. Both groups had significant reductions in alcohol consumption over time and high-treatment engagement rates. Both oral and injectable formulations are feasible to initiate prior to discharge for hospital inpatients identified as having an AUD.
Keyphrases
  • alcohol use disorder
  • alcohol consumption
  • healthcare
  • randomized controlled trial
  • emergency department
  • hyaluronic acid
  • tissue engineering
  • replacement therapy