Depression increases the genetic susceptibility to high body mass index: Evidence from UK Biobank.

Anwar MulugetaAng ZhouKarani S VimaleswaranCameron DicksonElina Hyppӧnen

Published in: Depression and anxiety (2019)

Genetic predisposition to high BMI was higher among depressed than to nondepressed individuals. This study provides support for a possible role of MC4R in the link between depression and obesity.

Keyphrases

body mass index
weight gain
depressive symptoms
genome wide
metabolic syndrome
insulin resistance
type diabetes
copy number
weight loss
physical activity
cross sectional
high fat diet induced
dna methylation
adipose tissue
skeletal muscle