The regulation effect of GLUT9/SLC2A9 on intrahepatic uric acid level and metabolic associated fatty liver disease.

Hang ZengChenxi TangBingru LinMengli YuXinyu WangJinghua WangShenghui ChenChaohui Yu

Published in: Hepatology international (2022)

Our results suggested that GLUT9 polymorphism was significantly associated with MAFLD, and hepatic-specific knockout of Glut9 significantly decreased intrahepatic contents and ameliorated diet-induced MAFLD in mice.

Keyphrases

uric acid
metabolic syndrome
high fat diet induced
wild type
adipose tissue
fatty acid