HLA expression as a risk factor for metastases of cutaneous squamous-cell carcinoma in organ- transplant recipients.

Estella de JongKoen D QuintAbdoelwaheb El GhalbzouriRobert M VerdijkJelle J GoemanSebastiaan HeidtFrans H J ClaasJohan W de FijterRoel E GendersMaarten H VermeerJan Nico Bouwes Bavinck

Published in: Human immunology (2023)

Contrary to immunocompetent patients, HLA-B/C expression tends to be upregulated in metastasized cSCC compared to non-metastasized cSCC in SOTR, suggesting that different tumor escape mechanisms play a role in SOTR compared to immunocompetent patients.

Keyphrases

squamous cell carcinoma
end stage renal disease
newly diagnosed
ejection fraction
poor prognosis
prognostic factors
radiation therapy
binding protein