The effects of aerobic exercise on neuroimmune responses in animals with traumatic peripheral nerve injury: a systematic review with meta-analyses.
Marije L S Sleijser-KoehorstMeghan A KoopMichel Willem CoppietersIvo J Lutke SchipholtNemanja RadisicCarlijn R HooijmansGwendolijne G M Scholten-PeetersPublished in: Journal of neuroinflammation (2023)
This review revealed widespread positive modulatory effects of aerobic exercise on neuroimmune responses following traumatic peripheral nerve injury. These changes are in line with a beneficial influence on pro-inflammatory processes and increased anti-inflammatory responses. Given the small sample sizes and the unclear risk of bias of the studies, results should be interpreted with caution.