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Enhanced production of interleukin-29 and related genes are associated with T helper 1 cell parameters in patients with type 2 diabetes mellitus.
Zahra Sardarmelli
Vida Sheikh
Ghasem Solgi
Mahdi Behzad
Published in:
Human immunology (2023)
Abnormal expression levels of IL-29- and Th1- related genes are linked with T2DM pathogenesis. IL-29 may amplify the expression of Th1-specific genes especially TNF-α by upregulating NFATc1 expression.
Keyphrases
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poor prognosis
rheumatoid arthritis
binding protein
type diabetes
regulatory t cells
dendritic cells
cell therapy
immune response
mesenchymal stem cells
metabolic syndrome
bone marrow