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Enhanced production of interleukin-29 and related genes are associated with T helper 1 cell parameters in patients with type 2 diabetes mellitus.

Zahra SardarmelliVida SheikhGhasem SolgiMahdi Behzad
Published in: Human immunology (2023)
Abnormal expression levels of IL-29- and Th1- related genes are linked with T2DM pathogenesis. IL-29 may amplify the expression of Th1-specific genes especially TNF-α by upregulating NFATc1 expression.
Keyphrases
  • poor prognosis
  • rheumatoid arthritis
  • binding protein
  • type diabetes
  • regulatory t cells
  • dendritic cells
  • cell therapy
  • immune response
  • mesenchymal stem cells
  • metabolic syndrome
  • bone marrow