Hypoacetylation of acetyl-histone H3 (H3K9ac) as marker of poor prognosis in oral cancer.
Liana P WebberVivian P WagnerMarina CurraPablo A VargasLuise MeurerVinícius C CarrardCristiane H SquarizeRogério M CastilhoManoela Domingues MartinsPublished in: Histopathology (2017)
The present findings suggest that changes in H3K9ac occur during the process of oral carcinogenesis along with an increase in cell proliferation and EMT. The results demonstrate that H3K9ac may be a useful novel prognostic marker for OSCC.