Clinicopathological and molecular implications of aberrant thyroid transcription factor-1 expression in colorectal carcinomas: an immunohistochemical analysis of 1319 cases using three different antibody clones.

Jeong Mo BaeJung Ho KimJeong Hwan ParkHye Eun ParkNam-Yun ChoGyeong Hoon Kang

Published in: Histopathology (2017)

Our study confirmed that the frequency and characteristics of aberrant TTF-1 expression in CRCs vary according to the antibody clone. Aberrant TTF-1 expression detected by clone SPT24 or SP141 may be encountered preferentially in distally located, conventional pathway-type CRCs.

Keyphrases

poor prognosis
transcription factor
binding protein
long non coding rna
single molecule