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GATA4 Forms a Positive Feedback Loop with CDX2 to Transactivate MUC2 in Bile Acids-Induced Gastric Intestinal Metaplasia.

Xiaofang YangTing YeLi RongHong PengJin TongXiao XiaoXiaoqiang WanJinjun Guo
Published in: Gut and liver (2023)
GATA4 is upregulated and can form a positive feedback loop with CDX2 to transactivate MUC2 in GIM. NF-κB signaling is involved in the upregulation of GATA4 by chenodeoxycholic acid.
Keyphrases
  • transcription factor
  • signaling pathway
  • high glucose
  • cell proliferation
  • diabetic rats
  • poor prognosis
  • pi k akt
  • lps induced
  • nuclear factor
  • immune response
  • long non coding rna