Effects of the DL76 Antagonist/Inverse Agonist of Histamine H 3 Receptors on Experimental Periodontitis in Rats: Morphological Studies.

Mariusz GeremekBogna DrozdzowskaDorota Łażewska Katarzyna Kieć-KononowiczJerzy Jochem

Published in: Pharmaceuticals (Basel, Switzerland) (2024)

DL76 is able to inhibit the progression of experimental periodontitis in rats, as demonstrated by a reduction in the inflammatory cell infiltration, a decrease in the RANKL/RANK OPG pathway expression and a reduction in the alveolar bone resorption.

Keyphrases

bone loss
poor prognosis
single cell
oxidative stress
cell therapy
bone mineral density
stem cells
binding protein
immune response
soft tissue
mesenchymal stem cells
bone marrow
body composition