Correlation Study on HLA-DR and CD117 (c-Kit) Expressions: Its Prognosis and Treatment Response in Acute Myeloid Leukemia Patients.

Yomna M El-MeliguiHeba E Abd ElrhmanAhmad SalahuddinManal Ali HamoudaAmira Bisher Kassem

Published in: Pharmacogenomics and personalized medicine (2021)

The current study suggested that the expression of CD117 and HLA-DR may be a prognostic marker in AML, as they are associated with M0, M1, and M2 FAB subtypes; moreover, patients with combined HLA-DR and CD117 positive expression are associated with CD34 expression and intermediate cytogenetic group.

Keyphrases

poor prognosis
end stage renal disease
nk cells
acute myeloid leukemia
binding protein
chronic kidney disease
newly diagnosed
ejection fraction
editorial comment
prognostic factors